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Inhibition Mechanism of an Anti-CRISPR Suppressor AcrIIA4 Targeting SpyCas9
Prokaryotic CRISPR-Cas adaptive immune systems utilize sequence specific RNA-guided endonucleases to defend against infection by viruses, bacteriophages and mobile elements, while these foreign genetic elements evolve diverse anti-CRISPR proteins to overcome the CRISPR-Cas-mediated defense of the ho...
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| Udgivet i: | Mol Cell |
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| Main Authors: | , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2017
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5595222/ https://ncbi.nlm.nih.gov/pubmed/28602637 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molcel.2017.05.024 |
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