Intrinsic disorder is essential for Cas9 inhibition of anti-CRISPR AcrIIA5

Clustered regularly interspaced short palindromic repeats (CRISPRs) and CRISPR-associated (Cas) proteins provide adaptive immunity to prokaryotes against invading phages and plasmids. As a countermeasure, phages have evolved anti-CRISPR (Acr) proteins that neutralize the CRISPR immunity. AcrIIA5, is...

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Vydáno v:Nucleic Acids Res
Hlavní autoři: An, So Young, Ka, Donghyun, Kim, Iktae, Kim, Eun-Hee, Kim, Nak-Kyoon, Bae, Euiyoung, Suh, Jeong-Yong
Médium: Artigo
Jazyk:Inglês
Vydáno: Oxford University Press 2020
Témata:
Structural Biology
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7367191/
https://ncbi.nlm.nih.gov/pubmed/32544231
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkaa512
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