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Developmental origin, functional maintenance and genetic rescue of osteoclasts
Osteoclasts are multinucleated giant cells that resorb bone, ensuring development and continuous remodelling of the skeleton and the bone marrow haematopoietic niche. Defective osteoclast activity leads to osteopetrosis and bone marrow failure(1–9), whereas excess activity can contribute to bone los...
में बचाया:
| में प्रकाशित: | Nature |
|---|---|
| मुख्य लेखकों: | , , , , , , , , , , , , , |
| स्वरूप: | Artigo |
| भाषा: | Inglês |
| प्रकाशित: |
2019
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| विषय: | |
| ऑनलाइन पहुंच: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6910203/ https://ncbi.nlm.nih.gov/pubmed/30971820 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41586-019-1105-7 |
| टैग : |
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