Specification of tissue-resident macrophages during organogenesis

Resident macrophages support embryonic development and tissue homeostasis and repair. The mechanisms that control their differentiation remain unclear. We report here that Erythro-Myeloid Progenitors generate pre-macrophages (pMacs) that simultaneously colonize the whole embryo from embryonic day (E...

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Detalhes bibliográficos
Publicado no:Science
Main Authors: Mass, Elvira, Ballesteros, Ivan, Farlik, Matthias, Halbritter, Florian, Günther, Patrick, Crozet, Lucile, Jacome-Galarza, Christian E., Händler, Kristian, Klughammer, Johanna, Kobayashi, Yasuhiro, Gomez-Perdiguero, Elisa, Schultze, Joachim L., Beyer, Marc, Bock, Christoph, Geissmann, Frederic
Formato: Artigo
Idioma:Inglês
Publicado em: 2016
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5066309/
https://ncbi.nlm.nih.gov/pubmed/27492475
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/science.aaf4238
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