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Systematic evaluation of error rates and causes in short samples in next-generation sequencing

Next-generation sequencing (NGS) is the method of choice when large numbers of sequences have to be obtained. While the technique is widely applied, varying error rates have been observed. We analysed millions of reads obtained after sequencing of one single sequence on an Illumina sequencer. Accord...

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Detalhes bibliográficos
Publicado no:Sci Rep
Principais autores: Pfeiffer, Franziska, Gröber, Carsten, Blank, Michael, Händler, Kristian, Beyer, Marc, Schultze, Joachim L., Mayer, Günter
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6053417/
https://ncbi.nlm.nih.gov/pubmed/30026539
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-018-29325-6
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