Control for stochastic sampling variation and qualitative sequencing error in next generation sequencing

BACKGROUND: Clinical implementation of Next-Generation Sequencing (NGS) is challenged by poor control for stochastic sampling, library preparation biases and qualitative sequencing error. To address these challenges we developed and tested two hypotheses. METHODS: Hypothesis 1: Analytical variation...

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Bibliografiske detaljer
Udgivet i:Biomol Detect Quantif
Main Authors: Blomquist, Thomas, Crawford, Erin L., Yeo, Jiyoun, Zhang, Xiaolu, Willey, James C.
Format: Artigo
Sprog:Inglês
Udgivet: Elsevier 2015
Fag:
Research Paper
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4673681/
https://ncbi.nlm.nih.gov/pubmed/26693143
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bdq.2015.08.003
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