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The Role of Replicates for Error Mitigation in Next-Generation Sequencing
Advances in next-generation technologies have rapidly improved sequencing fidelity and significantly decreased sequencing error rates. However, with billions of nucleotides in a human genome, even low experimental error rates yield many errors in variant calls. Erroneous variants can mimic true soma...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2013
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4103745/ https://ncbi.nlm.nih.gov/pubmed/24322726 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nrg3655 |
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