A somatic mutation in erythro-myeloid progenitors causes neurodegenerative disease

The pathophysiology of neurodegenerative diseases is poorly understood, and therapeutic options are few. Neurodegenerative diseases are hallmarked by progressive neuronal dysfunction and loss, associated with chronic glial activation(1). Whether microglial activation, which is viewed in general as a...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Nature
Prif Awduron: Mass, Elvira, Jacome-Galarza, Christian E., Blank, Thomas, Lazarov, Tomi, Durham, Benjamin H., Ozkaya, Neval, Pastore, Alessandro, Schwabenland, Marius, Chung, Young Rock, Rosenblum, Marc K., Prinz, Marco, Abdel-Wahab, Omar, Geissmann, Frederic
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: 2017
Pynciau:
Article
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC6047345/
https://ncbi.nlm.nih.gov/pubmed/28854169
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nature23672
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