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CSF1R regulates the dendritic cell pool size in adult mice via embryo-derived tissue-resident macrophages
Regulatory mechanisms controlling the pool size of spleen dendritic cells (DC) remain incompletely understood. DCs are continuously replenished from hematopoietic stem cells, and FLT3-mediated signals cell-intrinsically regulate homeostatic expansion of spleen DCs. Here we show that combining FLT3 a...
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| Veröffentlicht in: | Nat Commun |
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| Hauptverfasser: | , , , , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
Nature Publishing Group UK
2018
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6290072/ https://ncbi.nlm.nih.gov/pubmed/30538245 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-018-07685-x |
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