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CSF1R regulates the dendritic cell pool size in adult mice via embryo-derived tissue-resident macrophages

Regulatory mechanisms controlling the pool size of spleen dendritic cells (DC) remain incompletely understood. DCs are continuously replenished from hematopoietic stem cells, and FLT3-mediated signals cell-intrinsically regulate homeostatic expansion of spleen DCs. Here we show that combining FLT3 a...

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Detalhes bibliográficos
Publicado no:Nat Commun
Main Authors: Percin, Gulce Itir, Eitler, Jiri, Kranz, Andrea, Fu, Jun, Pollard, Jeffrey W., Naumann, Ronald, Waskow, Claudia
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6290072/
https://ncbi.nlm.nih.gov/pubmed/30538245
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-018-07685-x
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