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Regulation of lysosome biogenesis and functions in osteoclasts
In order to resorb the mineralized bone extracellular matrix, the osteoclast relies on the generation of a resorption lacuna characterized by the presence of specific proteases and a low pH. Hence, bone resorption by osteoclasts is highly dependent on lysosomes, the organelles specialized in intra-...
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Main Authors: | , , |
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Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
Landes Bioscience
2013
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3899188/ https://ncbi.nlm.nih.gov/pubmed/23966172 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/cc.25825 |
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