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GGCX and VKORC1 inhibit osteocalcin endocrine functions
Osteocalcin (OCN) is an osteoblast-derived hormone favoring glucose homeostasis, energy expenditure, male fertility, brain development, and cognition. Before being secreted by osteoblasts in the bone extracellular matrix, OCN is γ-carboxylated by the γ-carboxylase (GGCX) on three glutamic acid resid...
Uloženo v:
| Vydáno v: | J Cell Biol |
|---|---|
| Hlavní autoři: | , , , , |
| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
The Rockefeller University Press
2015
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| Témata: | |
| On-line přístup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4362468/ https://ncbi.nlm.nih.gov/pubmed/25753038 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.201409111 |
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