Depletion of TRRAP induces p53-independent senescence in liver cancer by downregulating mitotic genes

Hepatocellular carcinoma (HCC) is an aggressive subtype of liver cancer with few effective treatments and the underlying mechanisms that drive HCC pathogenesis remain poorly characterized. Identifying genes and pathways essential for HCC cell growth will aid the development of new targeted therapies...

Täydet tiedot

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Bibliografiset tiedot
Julkaisussa:Hepatology
Päätekijät: Kwan, Suet-Yan, Sheel, Ankur, Song, Chun-Qing, Zhang, Xiao-Ou, Jiang, Tingting, Dang, Hien, Cao, Yueying, Ozata, Deniz M., Mou, Haiwei, Yin, Hao, Weng, Zhiping, Wang, Xin Wei, Xue, Wen
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: 2019
Aiheet:
Article
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC6906267/
https://ncbi.nlm.nih.gov/pubmed/31188495
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/hep.30807
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