Depletion of TRRAP induces p53-independent senescence in liver cancer by downregulating mitotic genes

Hepatocellular carcinoma (HCC) is an aggressive subtype of liver cancer with few effective treatments and the underlying mechanisms that drive HCC pathogenesis remain poorly characterized. Identifying genes and pathways essential for HCC cell growth will aid the development of new targeted therapies...

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Detalhes bibliográficos
Publicado no:Hepatology
Main Authors: Kwan, Suet-Yan, Sheel, Ankur, Song, Chun-Qing, Zhang, Xiao-Ou, Jiang, Tingting, Dang, Hien, Cao, Yueying, Ozata, Deniz M., Mou, Haiwei, Yin, Hao, Weng, Zhiping, Wang, Xin Wei, Xue, Wen
Formato: Artigo
Idioma:Inglês
Publicado em: 2019
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6906267/
https://ncbi.nlm.nih.gov/pubmed/31188495
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/hep.30807
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