Identification of α,β-Hydrolase Domain Containing Protein 6 as a Diacylglycerol Lipase in Neuro-2a Cells

The endocannabinoid 2-arachidonoylglycerol (2-AG) is involved in neuronal differentiation. This study aimed to identify the biosynthetic enzymes responsible for 2-AG production during retinoic acid (RA)-induced neurite outgrowth of Neuro-2a cells. First, we confirmed that RA stimulation of Neuro-2a...

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Détails bibliographiques
Publié dans:Front Mol Neurosci
Auteurs principaux: van Esbroeck, Annelot C. M., Kantae, Vasudev, Di, Xinyu, van der Wel, Tom, den Dulk, Hans, Stevens, Anna F., Singh, Simar, Bakker, Alexander T., Florea, Bogdan I., Stella, Nephi, Overkleeft, Herman S., Hankemeier, Thomas, van der Stelt, Mario
Format: Artigo
Langue:Inglês
Publié: Frontiers Media S.A. 2019
Sujets:
Neuroscience
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6901982/
https://ncbi.nlm.nih.gov/pubmed/31849602
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fnmol.2019.00286
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