Expedient Synthesis of Core Disaccharide Building Blocks from Natural Polysaccharides for Heparan Sulfate Oligosaccharide Assembly

The complex sulfation motifs of heparan sulfate glycosaminoglycans (HS GAGs) play critical roles in many important biological processes. However, an understanding of their specific functions has been hampered by an inability to synthesize large numbers of diverse, yet defined, HS structures. Here, w...

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Bibliografiske detaljer
Udgivet i:Angew Chem Int Ed Engl
Main Authors: Pawar, Nitin J., Wang, Lei, Higo, Takuya, Bhattacharya, Chandrabali, Kancharla, Pavan K., Zhang, Fuming, Baryal, Kedar, Huo, Chang-Xin, Liu, Jian, Linhardt, Robert J., Huang, Xuefei, Hsieh-Wilson, Linda C.
Format: Artigo
Sprog:Inglês
Udgivet: 2019
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6901730/
https://ncbi.nlm.nih.gov/pubmed/31553820
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/anie.201908805
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