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Adeno-associated virus capsid protein expression in Escherichia coli and chemically defined capsid assembly

Research and clinical applications of recombinant adeno-associated virus (rAAV) significantly increased in recent years alongside regulatory approvals of rAAV gene therapy products. To date, all rAAV vectors as well as AAV empty capsids are produced in eukaryotic cells. We explored a new route to ge...

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Vydáno v:Sci Rep
Hlavní autoři: Le, Dinh To, Radukic, Marco T., Müller, Kristian M.
Médium: Artigo
Jazyk:Inglês
Vydáno: Nature Publishing Group UK 2019
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6901487/
https://ncbi.nlm.nih.gov/pubmed/31819093
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-019-54928-y
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