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Adeno-associated virus capsid protein expression in Escherichia coli and chemically defined capsid assembly

Research and clinical applications of recombinant adeno-associated virus (rAAV) significantly increased in recent years alongside regulatory approvals of rAAV gene therapy products. To date, all rAAV vectors as well as AAV empty capsids are produced in eukaryotic cells. We explored a new route to ge...

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Bibliografiske detaljer
Udgivet i:Sci Rep
Main Authors: Le, Dinh To, Radukic, Marco T., Müller, Kristian M.
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group UK 2019
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6901487/
https://ncbi.nlm.nih.gov/pubmed/31819093
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-019-54928-y
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