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Adeno-associated virus capsid protein expression in Escherichia coli and chemically defined capsid assembly
Research and clinical applications of recombinant adeno-associated virus (rAAV) significantly increased in recent years alongside regulatory approvals of rAAV gene therapy products. To date, all rAAV vectors as well as AAV empty capsids are produced in eukaryotic cells. We explored a new route to ge...
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| Pubblicato in: | Sci Rep |
|---|---|
| Autori principali: | , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
Nature Publishing Group UK
2019
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6901487/ https://ncbi.nlm.nih.gov/pubmed/31819093 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-019-54928-y |
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