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Adeno-associated virus capsid protein expression in Escherichia coli and chemically defined capsid assembly

Research and clinical applications of recombinant adeno-associated virus (rAAV) significantly increased in recent years alongside regulatory approvals of rAAV gene therapy products. To date, all rAAV vectors as well as AAV empty capsids are produced in eukaryotic cells. We explored a new route to ge...

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Bibliografiska uppgifter
I publikationen:Sci Rep
Huvudupphovsmän: Le, Dinh To, Radukic, Marco T., Müller, Kristian M.
Materialtyp: Artigo
Språk:Inglês
Publicerad: Nature Publishing Group UK 2019
Ämnen:
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC6901487/
https://ncbi.nlm.nih.gov/pubmed/31819093
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-019-54928-y
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