CXCR3 Identifies Human Naive CD8(+) T Cells with Enhanced Effector Differentiation Potential

In mice, the ability of naive T (T(N)) cells to mount an effector response correlates with TCR sensitivity for self-derived Ags, which can be quantified indirectly by measuring surface expression levels of CD5. Equivalent findings have not been reported previously in humans. We identified two discre...

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Detaylı Bibliyografya
Yayımlandı:J Immunol
Asıl Yazarlar: De Simone, Gabriele, Mazza, Emilia M. C., Cassotta, Antonino, Davydov, Alexey N., Kuka, Mirela, Zanon, Veronica, De Paoli, Federica, Scamardella, Eloise, Metsger, Maria, Roberto, Alessandra, Pilipow, Karolina, Colombo, Federico S., Tenedini, Elena, Tagliafico, Enrico, Gattinoni, Luca, Mavilio, Domenico, Peano, Clelia, Price, David A., Singh, Satya P., Farber, Joshua M., Serra, Valentina, Cucca, Francesco, Ferrari, Francesco, Orrù, Valeria, Fiorillo, Edoardo, Iannacone, Matteo, Chudakov, Dmitriy M., Sallusto, Federica, Lugli, Enrico
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: AAI 2019
Konular:
Clinical and Human Immunology
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC6900484/
https://ncbi.nlm.nih.gov/pubmed/31740485
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1901072
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