Curtailed T‐cell activation curbs effector differentiation and generates CD8(+) T cells with a naturally‐occurring memory stem cell phenotype

Human T memory stem (T(SCM)) cells with superior persistence capacity and effector functions are emerging as important players in the maintenance of long‐lived T‐cell memory and are thus considered an attractive population to be used in adoptive transfer‐based immunotherapy of cancer. However, the m...

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Vydáno v:Eur J Immunol
Hlavní autoři: Zanon, Veronica, Pilipow, Karolina, Scamardella, Eloise, De Paoli, Federica, De Simone, Gabriele, Price, David A., Martinez Usatorre, Amaia, Romero, Pedro, Mavilio, Domenico, Roberto, Alessandra, Lugli, Enrico
Médium: Artigo
Jazyk:Inglês
Vydáno: John Wiley and Sons Inc. 2017
Témata:
Adaptive immunity
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5601228/
https://ncbi.nlm.nih.gov/pubmed/28671275
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/eji.201646732
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