Curtailed T‐cell activation curbs effector differentiation and generates CD8(+) T cells with a naturally‐occurring memory stem cell phenotype

Human T memory stem (T(SCM)) cells with superior persistence capacity and effector functions are emerging as important players in the maintenance of long‐lived T‐cell memory and are thus considered an attractive population to be used in adoptive transfer‐based immunotherapy of cancer. However, the m...

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Detalhes bibliográficos
Publicado no:Eur J Immunol
Main Authors: Zanon, Veronica, Pilipow, Karolina, Scamardella, Eloise, De Paoli, Federica, De Simone, Gabriele, Price, David A., Martinez Usatorre, Amaia, Romero, Pedro, Mavilio, Domenico, Roberto, Alessandra, Lugli, Enrico
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2017
Assuntos:
Adaptive immunity
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5601228/
https://ncbi.nlm.nih.gov/pubmed/28671275
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/eji.201646732
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