CXCR3 Identifies Human Naive CD8(+) T Cells with Enhanced Effector Differentiation Potential

In mice, the ability of naive T (T(N)) cells to mount an effector response correlates with TCR sensitivity for self-derived Ags, which can be quantified indirectly by measuring surface expression levels of CD5. Equivalent findings have not been reported previously in humans. We identified two discre...

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Detalhes bibliográficos
Publicado no:J Immunol
Main Authors: De Simone, Gabriele, Mazza, Emilia M. C., Cassotta, Antonino, Davydov, Alexey N., Kuka, Mirela, Zanon, Veronica, De Paoli, Federica, Scamardella, Eloise, Metsger, Maria, Roberto, Alessandra, Pilipow, Karolina, Colombo, Federico S., Tenedini, Elena, Tagliafico, Enrico, Gattinoni, Luca, Mavilio, Domenico, Peano, Clelia, Price, David A., Singh, Satya P., Farber, Joshua M., Serra, Valentina, Cucca, Francesco, Ferrari, Francesco, Orrù, Valeria, Fiorillo, Edoardo, Iannacone, Matteo, Chudakov, Dmitriy M., Sallusto, Federica, Lugli, Enrico
Formato: Artigo
Idioma:Inglês
Publicado em: AAI 2019
Assuntos:
Clinical and Human Immunology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6900484/
https://ncbi.nlm.nih.gov/pubmed/31740485
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1901072
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