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A flexible design for advanced Phase I/II clinical trials with continuous efficacy endpoints
There is growing interest in integrated Phase I/II oncology clinical trials involving molecularly targeted agents (MTA). One of the main challenges of these trials are nontrivial dose–efficacy relationships and administration of MTAs in combination with other agents. While some designs were recently...
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| Publicado no: | Biom J |
|---|---|
| Main Authors: | , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
John Wiley and Sons Inc.
2019
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6899762/ https://ncbi.nlm.nih.gov/pubmed/31298770 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/bimj.201800313 |
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