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Sharp kinking of a coiled-coil in MutS allows DNA binding and release

DNA mismatch repair (MMR) corrects mismatches, small insertions and deletions in DNA during DNA replication. While scanning for mismatches, dimers of MutS embrace the DNA helix with their lever and clamp domains. Previous studies indicated generic flexibility of the lever and clamp domains of MutS p...

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Bibliografski detalji
Izdano u:Nucleic Acids Res
Glavni autori: Bhairosing-Kok, Doreth, Groothuizen, Flora S, Fish, Alexander, Dharadhar, Shreya, Winterwerp, Herrie H K, Sixma, Titia K
Format: Artigo
Jezik:Inglês
Izdano: Oxford University Press 2019
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6895276/
https://ncbi.nlm.nih.gov/pubmed/31372631
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkz649
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