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Dual role of MutS glutamate 38 in DNA mismatch discrimination and in the authorization of repair
MutS plays a critical role in DNA mismatch repair in Escherichia coli by binding to mismatches and initiating repair in an ATP-dependent manner. Mutational analysis of a highly conserved glutamate, Glu38, has revealed its role in mismatch recognition by enabling MutS to discriminate between homodupl...
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| Main Authors: | , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2006
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1383519/ https://ncbi.nlm.nih.gov/pubmed/16407973 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.emboj.7600936 |
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