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Dual role of MutS glutamate 38 in DNA mismatch discrimination and in the authorization of repair

MutS plays a critical role in DNA mismatch repair in Escherichia coli by binding to mismatches and initiating repair in an ATP-dependent manner. Mutational analysis of a highly conserved glutamate, Glu38, has revealed its role in mismatch recognition by enabling MutS to discriminate between homodupl...

詳細記述

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書誌詳細
主要な著者: Lebbink, Joyce H G, Georgijevic, Dubravka, Natrajan, Ganesh, Fish, Alexander, Winterwerp, Herrie H K, Sixma, Titia K, de Wind, Niels
フォーマット: Artigo
言語:Inglês
出版事項: 2006
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC1383519/
https://ncbi.nlm.nih.gov/pubmed/16407973
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.emboj.7600936
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