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MutS/MutL crystal structure reveals that the MutS sliding clamp loads MutL onto DNA
To avoid mutations in the genome, DNA replication is generally followed by DNA mismatch repair (MMR). MMR starts when a MutS homolog recognizes a mismatch and undergoes an ATP-dependent transformation to an elusive sliding clamp state. How this transient state promotes MutL homolog recruitment and a...
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| הוצא לאור ב: | eLife |
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| Main Authors: | , , , , , , , , , , , , |
| פורמט: | Artigo |
| שפה: | Inglês |
| יצא לאור: |
eLife Sciences Publications, Ltd
2015
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| נושאים: | |
| גישה מקוונת: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4521584/ https://ncbi.nlm.nih.gov/pubmed/26163658 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.06744 |
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