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Deaminative Arylation of Amino Acid-derived Pyridinium Salts

A Suzuki–Miyaura cross-coupling of α-pyridinium esters and arylboroxines has been developed. Combined with formation of the pyridinium salts from amino acid derivatives, this method enables amino acid derivatives to be efficiently transformed into α-aryl esters and amides. Under the mild conditions,...

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Bibliographic Details
Published in:Org Lett
Main Authors: Hoerrner, Megan E., Baker, Kristen M., Basch, Corey H., Bampo, Earl M., Watson, Mary P.
Format: Artigo
Language:Inglês
Published: 2019
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6894616/
https://ncbi.nlm.nih.gov/pubmed/31464131
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.orglett.9b02643
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