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Nickel-Catalyzed Synthesis of Dialkyl Ketones from the Coupling of N-Alkyl Pyridinium Salts with Activated Carboxylic Acids
While ketones are among the most versatile functional groups, their synthesis remains reliant upon reactive and low abundance starting materials. In contrast, amide formation is the most-used bond construction in medicinal chemistry because the chemistry is reliable and draws upon large, diverse sub...
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| Publicado no: | Angew Chem Int Ed Engl |
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| Main Authors: | , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2020
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7397811/ https://ncbi.nlm.nih.gov/pubmed/32374951 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/anie.202002271 |
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