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Nickel-Catalyzed Synthesis of Dialkyl Ketones from the Coupling of N-Alkyl Pyridinium Salts with Activated Carboxylic Acids

While ketones are among the most versatile functional groups, their synthesis remains reliant upon reactive and low abundance starting materials. In contrast, amide formation is the most-used bond construction in medicinal chemistry because the chemistry is reliable and draws upon large, diverse sub...

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Vydáno v:Angew Chem Int Ed Engl
Hlavní autoři: Wang, Jiang, Hoerrner, Megan E., Watson, Mary P., Weix, Daniel J.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2020
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7397811/
https://ncbi.nlm.nih.gov/pubmed/32374951
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/anie.202002271
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