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Harnessing Alkyl Pyridinium Salts as Electrophiles in Deaminative Alkyl-Alkyl Cross-Couplings

A Negishi cross-coupling of alkyl pyridinium salts and alkylzinc halides has been developed. This is the first example of alkyl–alkyl bond formation via cross-coupling of an alkyl amine derivative with an unactivated alkyl group, and allows both primary and secondary alkyl pyridinium salts to react...

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Détails bibliographiques
Publié dans:J Am Chem Soc
Auteurs principaux: Plunkett, Shane, Basch, Corey H., Santana, Samantha O., Watson, Mary P.
Format: Artigo
Langue:Inglês
Publié: 2019
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6434706/
https://ncbi.nlm.nih.gov/pubmed/30682254
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/jacs.9b00111
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