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Deaminative Reductive Cross-Electrophile Couplings of Alkylpyridinium Salts and Aryl Bromides

A nickel-catalyzed reductive cross-coupling of alkylpyridinium salts and aryl bromides has been developed using Mn as the reductant. Both primary and secondary alkylpyridinium salts can be used, and high functional group and heterocycle tolerance is observed, including for protic groups. Mechanistic...

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Dettagli Bibliografici
Pubblicato in:Org Lett
Autori principali: Liao, Jennie, Basch, Corey H., Hoerrner, Megan E., Talley, Michael R., Boscoe, Brian P., Tucker, Joseph W., Garnsey, Michelle R., Watson, Mary P.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2019
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6517243/
https://ncbi.nlm.nih.gov/pubmed/30917282
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.orglett.9b01014
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