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Deaminative Reductive Cross-Electrophile Couplings of Alkylpyridinium Salts and Aryl Bromides

A nickel-catalyzed reductive cross-coupling of alkylpyridinium salts and aryl bromides has been developed using Mn as the reductant. Both primary and secondary alkylpyridinium salts can be used, and high functional group and heterocycle tolerance is observed, including for protic groups. Mechanistic...

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Detalhes bibliográficos
Publicado no:Org Lett
Main Authors: Liao, Jennie, Basch, Corey H., Hoerrner, Megan E., Talley, Michael R., Boscoe, Brian P., Tucker, Joseph W., Garnsey, Michelle R., Watson, Mary P.
Formato: Artigo
Idioma:Inglês
Publicado em: 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6517243/
https://ncbi.nlm.nih.gov/pubmed/30917282
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.orglett.9b01014
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