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Nickel-Catalyzed Synthesis of Dialkyl Ketones from the Coupling of N-Alkyl Pyridinium Salts with Activated Carboxylic Acids
While ketones are among the most versatile functional groups, their synthesis remains reliant upon reactive and low abundance starting materials. In contrast, amide formation is the most-used bond construction in medicinal chemistry because the chemistry is reliable and draws upon large, diverse sub...
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| Publicat a: | Angew Chem Int Ed Engl |
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| Autors principals: | , , , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
2020
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7397811/ https://ncbi.nlm.nih.gov/pubmed/32374951 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/anie.202002271 |
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