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Enhanced Generation of Intraluminal Vesicles in Neuronal Late Endosomes in the Brain of a Down Syndrome Mouse Model with Endosomal Dysfunction
Down syndrome (DS) is a human genetic disease caused by trisomy of chromosome 21 and characterized by early developmental brain abnormalities. Dysfunctional endosomal pathway in neurons is an early event of DS and Alzheimer’s disease. Recently, we have demonstrated that exosome secretion is upregula...
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| Publicat a: | Dev Neurobiol |
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| Autors principals: | , , , , , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
2019
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6894426/ https://ncbi.nlm.nih.gov/pubmed/31278881 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/dneu.22708 |
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