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Roles for ER:endosome membrane contact sites in ligand-stimulated intraluminal vesicle formation

Multivesicular endosomes/bodies (MVBs) sort membrane proteins between recycling and degradative pathways. Segregation of membrane proteins onto intraluminal vesicles (ILVs) of MVBs removes them from the recycling pathway and facilitates their degradation following fusion of MVBs with lysosomes. Sort...

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Библиографические подробности
Опубликовано в: :Biochem Soc Trans
Главные авторы: Wong, Louise H., Eden, Emily R., Futter, Clare E.
Формат: Artigo
Язык:Inglês
Опубликовано: Portland Press Ltd. 2018
Предметы:
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC6195632/
https://ncbi.nlm.nih.gov/pubmed/30242114
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1042/BST20170432
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