Mitovesicles are a novel population of extracellular vesicles of mitochondrial origin altered in Down syndrome

Mitochondrial dysfunction is an established hallmark of aging and neurodegenerative disorders such as Down syndrome (DS) and Alzheimer’s disease (AD). Using a high-resolution density gradient separation of extracellular vesicles (EVs) isolated from murine and human DS and diploid control brains, we...

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Detalhes bibliográficos
Publicado no:Sci Adv
Main Authors: D’Acunzo, Pasquale, Pérez-González, Rocío, Kim, Yohan, Hargash, Tal, Miller, Chelsea, Alldred, Melissa J., Erdjument-Bromage, Hediye, Penikalapati, Sai C., Pawlik, Monika, Saito, Mitsuo, Saito, Mariko, Ginsberg, Stephen D., Neubert, Thomas A., Goulbourne, Chris N., Levy, Efrat
Formato: Artigo
Idioma:Inglês
Publicado em: American Association for the Advancement of Science 2021
Assuntos:
Research Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7880603/
https://ncbi.nlm.nih.gov/pubmed/33579698
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/sciadv.abe5085
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