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Quantitative Comparison of Proteomes Using SILAC

Stable isotope labeling by amino acids in cell culture (SILAC) has become very popular as a quantitative proteomic method since it was firstly introduced by Matthias Mann’s group in 2002. It is a metabolic labeling strategy in which isotope-labeled amino acids are metabolically incorporated in vivo...

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Detalhes bibliográficos
Publicado no:Curr Protoc Protein Sci
Main Authors: Deng, Jingjing, Erdjument-Bromage, Hediye, Neubert, Thomas A.
Formato: Artigo
Idioma:Inglês
Publicado em: 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6342620/
https://ncbi.nlm.nih.gov/pubmed/30238645
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/cpps.74
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