Tumor microenvironment dictates regulatory T cell phenotype: Upregulated immune checkpoints reinforce suppressive function

BACKGROUND: Regulatory T (T(reg)) cells have an immunosuppressive function in cancer, but the underlying mechanism of immunosuppression in the tumor microenvironment (TME) is unclear. METHODS: We compared the phenotypes of T cell subsets, including T(reg) cells, obtained from peripheral blood, malig...

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Detaylı Bibliyografya
Yayımlandı:J Immunother Cancer
Asıl Yazarlar: Kim, Hye Ryun, Park, Hyo Jin, Son, Jimin, Lee, Jin Gu, Chung, Kyung Young, Cho, Nam Hoon, Shim, Hyo Sup, Park, Seyeon, Kim, Gamin, In Yoon, Hong, Kim, Hyun Gyung, Jung, Yong Woo, Cho, Byoung Chul, Park, Seong Yong, Rha, Sun Young, Ha, Sang-Jun
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: BioMed Central 2019
Konular:
Research Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC6894345/
https://ncbi.nlm.nih.gov/pubmed/31801611
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s40425-019-0785-8
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