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Molecular subtypes of oropharyngeal cancer show distinct immune microenvironment related with immune checkpoint blockade response

BACKGROUND: Oropharyngeal cancer (OPC) exhibits diverse immunological properties; however, their implications for immunotherapy are unknown. METHODS: We analysed 37 surgically resected and nine recurrent or metastatic anti-programmed death-1 (PD-1)/programmed death-ligand 1 (PD-L1)-treated OPC tumou...

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Foilsithe in:Br J Cancer
Main Authors: Kim, Min Hwan, Kim, Jae-Hwan, Lee, Ji Min, Choi, Jae Woo, Jung, Dongmin, Cho, Hojin, Kang, Hyundeok, Hong, Min Hee, Heo, Su Jin, Kim, Se Heon, Choi, Eun Chang, Kim, Da Hee, Park, Young Min, Kim, Sangwoo, Yoon, Sun Och, Koh, Yoon Woo, Cho, Byoung Chul, Kim, Hye Ryun
Formáid: Artigo
Teanga:Inglês
Foilsithe: Nature Publishing Group UK 2020
Ábhair:
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC7251088/
https://ncbi.nlm.nih.gov/pubmed/32235905
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41416-020-0796-8
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