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Gly45 and Phe555 in Transmembrane Domains 1 and 10 are Critical for the Activation of OATP1B3 by Epigallocatechin Gallate
Organic anion transporting polypeptides (OATPs) 1B1 and 1B3 are two highly homologous transporters expressed in the human liver. However, epigallocatechin gallate (EGCG) which is the most predominant catechin in green tea has opposite effects on the function of OATP1B1 and 1B3. In the present study,...
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| Опубликовано в: : | J Agric Food Chem |
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| Главные авторы: | , , , , , , , |
| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
2019
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6892160/ https://ncbi.nlm.nih.gov/pubmed/31353905 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.jafc.9b03812 |
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