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Role of transmembrane domain 10 for the function of organic anion transporting polypeptide 1B1

The liver-specific organic anion transporting polypeptides OATP1B1 and OATP1B3 are highly homologous and share numerous substrates. However, at low concentrations OATP1B1 shows substrate selectivity for estrone-3-sulfate. In this study, we investigated the molecular mechanism for this substrate sele...

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Detalhes bibliográficos
Main Authors: Gui, Chunshan, Hagenbuch, Bruno
Formato: Artigo
Idioma:Inglês
Publicado em: Wiley Subscription Services, Inc., A Wiley Company 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2788284/
https://ncbi.nlm.nih.gov/pubmed/19760661
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/pro.240
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