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Amino Acid Residues in Transmembrane Domain 10 of Organic Anion Transporting Polypeptide 1B3 are Critical for Cholecystokinin Octapeptide Transport

Human organic anion transporting polypeptides (OATP) 1B1 and 1B3 are multi-specific transporters that mediate uptake of amphipathic organic compounds into hepatocytes. The two OATPs contain twelve transmembrane domains (TMs) and share 80% amino acid sequence identity. Besides common substrates with...

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Detalles Bibliográficos
Main Authors: Gui, Chunshan, Hagenbuch, Bruno
Formato: Artigo
Idioma:Inglês
Publicado: 2008
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC2628557/
https://ncbi.nlm.nih.gov/pubmed/18690707
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bi8008455
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