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Cloning/Characterization of the Canine Organic Anion Transporting Polypeptide 1b4 (Oatp1b4) and Classification of the Canine OATP/SLCO Members

The human liver specific organic anion transporting polypeptides (OATPs) 1B1 and 1B3 are involved in the elimination of numerous xenobiotics and drugs. Although dogs are frequently used for toxicologic and pharmacokinetic characterization of novel drugs, nothing is known about their OATP1B1/1B3 orth...

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Detalhes bibliográficos
Main Authors: Gui, Chunshan, Hagenbuch, Bruno
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2822128/
https://ncbi.nlm.nih.gov/pubmed/20079461
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cbpc.2010.01.005
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