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Transport by OATP1B1 and OATP1B3 Enhances the Cytotoxicity of Epigallocatechin 3-O-gallate and Several Quercetin Derivatives

Organic anion transporting polypeptide (OATP) 1B1 and 1B3 are transporters that are expressed selectively in human hepatocytes under normal conditions. OATP1B3 is also expressed in certain cancers. Flavonoids such as green tea catechins and quercetin glycosides have been shown to modulate the functi...

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Detalhes bibliográficos
Main Authors: Zhang, Yuchen, Hays, Amanda, Noblett, Alexander, Thapa, Mahendra, Hua, Duy H., Hagenbuch, Bruno
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3606651/
https://ncbi.nlm.nih.gov/pubmed/23327877
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/np3007292
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