Effect of pregnane X receptor ligands on transport mediated by human OATP1B1 and OATP1B3

The pregnane X receptor is a ligand-activated transcription factor that is abundantly expressed in hepatocytes. Numerous drugs are pregnane X receptor ligands. To bind to their receptor they must cross the sinusoidal membrane. Organic anion transporting polypeptides 1B1 and 1B3 (OATP1B1 and OATP1B3)...

Popoln opis

Shranjeno v:
Bibliografske podrobnosti
Main Authors: Gui, Chunshan, Miao, Yi, Thompson, Lucas, Wahlgren, Bret, Mock, Melissa, Stieger, Bruno, Hagenbuch, Bruno
Format: Artigo
Jezik:Inglês
Izdano: 2008
Teme:
Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC2376123/
https://ncbi.nlm.nih.gov/pubmed/18321482
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ejphar.2008.01.042
Oznake: Označite
Brez oznak, prvi označite!

Podobne knjige/članki