טוען...
Effect of pregnane X receptor ligands on transport mediated by human OATP1B1 and OATP1B3
The pregnane X receptor is a ligand-activated transcription factor that is abundantly expressed in hepatocytes. Numerous drugs are pregnane X receptor ligands. To bind to their receptor they must cross the sinusoidal membrane. Organic anion transporting polypeptides 1B1 and 1B3 (OATP1B1 and OATP1B3)...
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| Main Authors: | , , , , , , |
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| פורמט: | Artigo |
| שפה: | Inglês |
| יצא לאור: |
2008
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| נושאים: | |
| גישה מקוונת: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2376123/ https://ncbi.nlm.nih.gov/pubmed/18321482 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ejphar.2008.01.042 |
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