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Screening of X-ray responsive substances for the next generation of radiosensitizers

X-ray responsivity resulting in the generation of reactive oxygen species (ROS) was investigated in 9600 organic compounds that were selected by considering their structural diversity. We focused on superoxides that were primarily detected using dihydroethidium (DHE) and hydroxyl radicals, that were...

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Dettagli Bibliografici
Pubblicato in:Sci Rep
Autori principali: Moriyama, Akihiro, Hasegawa, Takema, Jiang, Lei, Iwahashi, Hitoshi, Mori, Takashi, Takahashi, Junko
Natura: Artigo
Lingua:Inglês
Pubblicazione: Nature Publishing Group UK 2019
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6890787/
https://ncbi.nlm.nih.gov/pubmed/31796788
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-019-54649-2
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