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Screening of X-ray responsive substances for the next generation of radiosensitizers

X-ray responsivity resulting in the generation of reactive oxygen species (ROS) was investigated in 9600 organic compounds that were selected by considering their structural diversity. We focused on superoxides that were primarily detected using dihydroethidium (DHE) and hydroxyl radicals, that were...

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Publicat a:Sci Rep
Autors principals: Moriyama, Akihiro, Hasegawa, Takema, Jiang, Lei, Iwahashi, Hitoshi, Mori, Takashi, Takahashi, Junko
Format: Artigo
Idioma:Inglês
Publicat: Nature Publishing Group UK 2019
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6890787/
https://ncbi.nlm.nih.gov/pubmed/31796788
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-019-54649-2
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