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Transcriptome Analysis of Porphyrin-Accumulated and X-Ray-Irradiated Cell Cultures under Limited Proliferation and Non-Lethal Conditions

5-Aminolevulinic acid (ALA) is a precursor of the photosensitizer used in photodynamic therapy. It accumulates in tumor cells and subsequently metabolizes to protoporphyrin IX (PpIX), which generates singlet oxygen after light irradiation. PpIX enhances the generation of reactive oxygen species foll...

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Detalhes bibliográficos
Publicado no:Microarrays (Basel)
Main Authors: Takahashi, Junko, Misawa, Masaki, Iwahashi, Hitoshi
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4996386/
https://ncbi.nlm.nih.gov/pubmed/27600211
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/microarrays4010025
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