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Screening of X-ray responsive substances for the next generation of radiosensitizers

X-ray responsivity resulting in the generation of reactive oxygen species (ROS) was investigated in 9600 organic compounds that were selected by considering their structural diversity. We focused on superoxides that were primarily detected using dihydroethidium (DHE) and hydroxyl radicals, that were...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Moriyama, Akihiro, Hasegawa, Takema, Jiang, Lei, Iwahashi, Hitoshi, Mori, Takashi, Takahashi, Junko
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6890787/
https://ncbi.nlm.nih.gov/pubmed/31796788
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-019-54649-2
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