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Screening of X-ray responsive substances for the next generation of radiosensitizers

X-ray responsivity resulting in the generation of reactive oxygen species (ROS) was investigated in 9600 organic compounds that were selected by considering their structural diversity. We focused on superoxides that were primarily detected using dihydroethidium (DHE) and hydroxyl radicals, that were...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:Sci Rep
Hauptverfasser: Moriyama, Akihiro, Hasegawa, Takema, Jiang, Lei, Iwahashi, Hitoshi, Mori, Takashi, Takahashi, Junko
Format: Artigo
Sprache:Inglês
Veröffentlicht: Nature Publishing Group UK 2019
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6890787/
https://ncbi.nlm.nih.gov/pubmed/31796788
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-019-54649-2
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